QUINALDINE

PRODUCT IDENTIFICATION
CAS NO. 91-63-4

QUINALDINE
EINECS NO. 202-085-1
FORMULA C10H9N
MOL WT. 143.19
H.S. CODE  
TOXICITY Oral rat LD50: 1230 mg/kg
SYNONYMS 2-Methylchinolin; 2-Methylquinoline; Chinaldine; Khinaldin;
SMILES Crotonaldehyde

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE clear to yellow oily liquid
MELTING POINT -2 C
BOILING POINT 248 C
SPECIFIC GRAVITY 1.058
SOLUBILITY IN WATER Insoluble
AUTOIGNITION  
pH  
VAPOR DENSITY 4.9
NFPA RATINGS  

REFRACTIVE INDEX

 1.8116
FLASH POINT

79 C
STABILITY Stable under ordinary conditions

GENERAL DESCRIPTION & APPLICATIONS
Quinoline, 1-azanaphthalene, is an aromatic nitrogen compound characterized by a solid-ring structure contains a benzene fused to pyridine at two adjacent carbon atoms. (Pyridine is a ring structure compound of five carbon atoms with a nitrogen atom). Quinoline itself is the simplest member of the quinoline. It is a hygroscopic, yellowish oily liquid; slightly soluble in water, soluble alcohol, ether, carbon disulfide and readily in many organic solvents. It can be obtained by the distillation of coal tar. Quinoline can be prepared from aniline with acrolein under heated sulfuric acid (Skraup synthesis). Various quinoline compounds can be prepared by Skraup synthesis series of different oxidizing agents. Isoquinoline differs from quinoline in nitrogen position (at 2). Quinoline family compounds are widely used as a parent compound to make drugs (especially anti-malarial medicines), fungicides, biocides, alkaloids, dyes, rubber chemicals and flavoring agents. They have antiseptic, antipyretic, and antiperiodic properties. They are also used as catalyst, corrosion inhibitor, preservative, and as solvent for resins and terpenes. They are used in transition-metal complex catalyst chemistry for uniform polymerization and luminescence chemistry. They are used as antifoaming agent in refinery field. Quinaldine, 2-methylquinoline, is used as an anti-malaria and preparing other anti-malaria drugs. It is used in manufacturing oil soluble dyes, food colorants, pharmaceuticals, pH indicators and other organic compounds. Quinaldic Acid is a carboxylic acid substituted quinoline at 2 position, a catabolite of tryptophan (aromatic side chain amino acid). Quinazoline, diazanaphthalene at 1,3 positions, is used as a chemical intermediate for making medicines and other organic compounds. It is a fundamental structure in some antihypertensive agents such as prazosin and doxazosin which are peripheral vasodilator. Quinoxaline, diazanaphthalene at 1,4 positions, is used as a chemical intermediate for making fungicides and other organic compounds.
SALES SPECIFICATION

APPEARANCE

 clear to yellow oily liquid

CONTENT

98.0% min

MOISTURE

0.5% max
TRANSPORTATION
PACKING  
HAZARD CLASS  
UN NO.

 
OTHER INFORMATION