SULFANILIC ACID

PRODUCT IDENTIFICATION
CAS NO. 121-57-3

SULFANILIC ACID

EINECS NO. 204-482-5
FORMULA (H2N)C6H4SO3H
MOL WT. 173.19
H.S. CODE 2921.42.2200
TOXICITY Oral rat LD50: 12,300 mg/kg
SYNONYMS 4-Aminobenzenesulfonic acid; p-Anilinesulfonic acid; Sulfanilic acid;
Kyselina Sulfanilova (Czech); Sulfanilsaeure (German); Aniline-p-sulfonic acid; 4-Sulfanilic acid; Aniline-4-sulfonic acid; Other RN: 856062-06-1
SMILES S(c1ccc(N)cc1)(O)(=O)=O

CLASSIFICATION

Benzenesulfonic acid, Aniline

EXTRA NOTES

 

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE light grey powder
MELTING POINT 288 C (Decomposes)
BOILING POINT  
SPECIFIC GRAVITY 1.485
SOLUBILITY IN WATER 1 g/100 ml
SOLVENT SOLUBILITY

 

AUTOIGNITION  
pKa 3.34
VAPOR DENSITY  
log P -2.16E+00 (Octanol-water)
VAPOR PRESSURE 2.02E-07 (mmHg at 25 C)
HENRY LAW CONSTANT 8.89E-13 (atm-m3/mole at 25 C)
OH RATE CONSTANT 2.32E-11 (cm3/molecule-sec at 25 C Atmospheric )
NFPA RATINGS Health: 1 Flammability: 1 Reactivity: 0

REFRACTIVE INDEX

  
FLASH POINT

 

STABILITY Stable under ordinary conditions

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Google Scholar Search

Drug Information Portal (U.S. National Library of Medicine) - Sulfanilic acid

PubChem Compound Summary - Sulfanilic acid

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Sulfanilic acid

http://www.ebi.ac.uk/ -  Sulfanilic acid

http://www.ncbi.nlm.nih.gov/ -  Sulfanilic acid

Material Safety Data Sheet

http://infohost.nmt.edu/
Preparation of the diazonium salt of sulfanilic acid: Although sulfanilic acid is insoluble in acid solutions, it is nevertheless necessary to carry out the diazotization reaction in an acid (HNO2, nitrous acid) solution. This problem can be circumvented by precipitating sulfanilic acid from a solution in which it is initially soluble. The precipitate which is formed is a fine suspension and reacts instantly with nitrous acid. The first step is to dissolve sulfanilic acid in basic solution.



http://www.akademiai.com/
Oxidation of sulfanilic acid to the corresponding azoxy derivative by peroxomonophosphoric acid (PMPA) has been studied in aqueous medium. The observed bell-shaped pH-rate profile has been rationalized on the basis of protonation of the amino group and ionization into different PMPA species and a suitable rate law has been proposed. The mechanism of oxidation involves the nucleophilic attack of nitrogen on the electrophilic peroxo oxygen.

Local:
Sulfanilic acid is a light grey powder or crystals; slightly soluble in water, alcohol, and ether, soluble in hot water and fuming hydrochloric acid, char at 288 - 300 C. Sulfanilic acid is a sulfonated aniline product. Aniline is the starting material in the dye manufacturing industry. Sulfonic acid and its salts present in organic dyes provide useful function of water solubility and or improve the washfastness of dyes due to their capabiltity of binding more tightly to the fabric. Sulfanilic acid is used as an intermediate for colorants (dyes, food colors, optical brightening agents), medicines and other organic synthesis. It is a component of griess reagent to determine nitrous acid. Sulfanilic acid is converted to sulfanilamide which is one of the basic materials to produce antibacterial sulfa drugs. There is an isomer called metanilic acid, sulfonic group at position 2. It is used in the manufacture of azo dyes and in synthesis sulfa drugs.
SALES SPECIFICATION

APPEARANCE

 light grey powder
PURITY

98.5% min

ANILINE

0.3% max

INSOLUBLES

0.1% max

TRANSPORTATION
PACKING  
HAZARD CLASS  
UN NO.

 

SAFETY INFORMATION

HAZARD OVERVIEW

May cause respiratory tract irritation. May cause allergic skin reaction. Causes eye and skin irritation. Target Organs: Skin

GHS

 
SIGNAL WORD Warning

PICTOGRAMS

HAZARD STATEMENTS

H319-H315-H317

P STATEMENTS

P280-P302 +P352

EC DIRECTIVES

 
HAZARD CODES

RISK PHRASES

36/38-43

SAFETY PHRASES

24-37




PRICE INFORMATION