COOMASSIE BRILLIANT BLUE R

Synonyms. Coomassie brilliant blue R; Hydrogen (4-(4-(p-ethoxyanilino)-4'-(ethyl(m- sulphonatobenzyl) amino) benzhydrylene)cyclohexa-2,5-dien-1- ylidene)(ethyl) (m-sulphonatobenzyl)ammonium monosodium salt; C.I. Acid Blue 83; Eriosin Brilliant Cyanine 6B; Coomassie Brilliant Blue R-250; Brilliant Indocyanine 6B; C.I.42660;

COOMASSIE BRILLIANT BLUE R

Click for original image

 

PRODUCT IDENTIFICATION

CAS RN

6104-59-2

EINECS RN

228-060-5

FORMULA

C45H44N3NaO7S2

MOLE WEIGHT

825.97

H.S CODE

 3204.19.2595

SMILES

 C(\c1ccc(N(Cc2cc(ccc2)S(=O)(=O)[O-])CC)cc1)(=C1/C=C\C(=[N+] (\Cc2 cc (ccc2)S(=O)(=O)[O-])CC)C=C1) c1ccc(Nc2ccc(OCC)cc2)cc1.[Na+]

CLASSIFICATION

Triarylmethane dye, Stain, Dye

EXTRA NOTES

Other RN: 12698-46-3, 86697-48-5, 108066-47-3

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

dark red-brown powder

MELTING POINT

 

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

Slightly soluble in hot water

SOLVENT SOLUBILITY

Slightly soluble in ethanol

VAPOR DENSITY

 

log P(octanol-water)

  

VAPOR PRESSURE

  

AUTOIGNITION TEMP

  
pK

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 1, Flammability: 0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - Coomassie brilliant blue R

Wikipedia Linking - Coomassie brilliant blue

Google Scholar Search - Coomassie brilliant blue R

U.S. National Library of Medicine - Coomassie brilliant blue R

PubChem Compound Summary - Coomassie brilliant blue R

NCBI (http://www.ncbi.nlm.nih.gov/) -  Coomassie brilliant blue R

Material Safety Data Sheet - Coomassie brilliant blue R

EPA - Substance Registry Services - Coomassie brilliant blue R

http://www.sigmaaldrich.com/
Brilliant Blue R has been used for many years for staining proteins on polyacrylamide electrophoresis gels. Improvement of sensitivity and background have been accomplished using Brilliant Blue dyes in a colloidal form. The Brilliant Blue R-Protein complex has an absorption maximum between 560 and 575 nm.3 (Scanning is usually done at 570 nm.) The staining intensity of proteins may be related to the basicity of the protein involved.

 

SALES SPECIFICATION

APPEARANCE

dark red-brown powder

DYE CONTENT

65% min

LOSS ON DRYING

5.0% max

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

 

HAZARD CLASS

 

PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

GHS (Globally Harmonised System) Classification: Not a dangerous substance. Potential Health Effects: Eyes - May cause eye irritation. Skin - May be harmful if absorbed through skin May cause skin irritation. Inhalation - May be harmful if inhaled. May cause respiratory tract irritation. Ingestion - May be harmful if swallowed.

HAZARD CODES

 

RISK PHRASES

 

SAFETY PHRASES

 

 

PACKING

Preserve in light-resistant and well-closed containers