CROCETIN DIGENTIOBIOSE ESTER

Synonyms. Crocin; Crocetin digentiobiose ester; 8,8'-Diapo-psi,psi-carotenedioic acid bis(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl) ester; Natural yellow 6; C.I. 75100; Bis(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl) 8,8'-diapo-psi,psi-carotenedioate; all-trans-Crocetin di-beta-D-gentiobiosyl ester; alpha-Crocin; Crocetin bis(gentiobiosyl) ester; Natural yellow 6; C.I. 75100; Yellow saffron; Crocus sativus;

CROCIN

Click for original image

 

PRODUCT IDENTIFICATION

CAS RN

42553-65-1

EINECS RN

255-881-6

FORMULA

C44H64O24

MOLE WEIGHT

976.96

H.S CODE

3204.19.4000

SMILES

O1[C@H]([C@@H]([C@@H](O)[C@@H](O)[C@H]1CO[C@H] 1[C@@H]([C@ H]([C@@H]([C@H](CO)O1)O)O)O)O) OC(\C(=C\C=C\C(=C\C=C \C=C( \C= C\C=C(\C(O[C@@H] 1O[C@@H]([C@@H](O)[C@@H](O )[C@H]1O) CO[C@H]1[C@H] (O)[C@@H](O)[C@H](O)[C@H](CO)O1)=O) C)C)C)C)=O

CLASSIFICATION

Food coloring, Carotenoid, Saffron, Aphrodisiac

EXTRA NOTES

General description:A highly unsaturared diterpene dicarboxylic acid ester found in saffron. Biochem/physiol Actions: Crocin alleviates some ethanol-induced impairments of learning and prevents ethanol-induced inhibition of hippocampal long-term potentiation (LTP), a form of activity-dependent synaptic plasticity that may underly learning and memory. Related CNS effects are specific to the digentiobiose ester; crocetin glucose gentiobiose ester is half as potent, and the diglucose ester has no effect at all. (sigmaaldrich)
Other RN: 1329-79-9, 11012-59-2, 52841-81-3, 53178-29-3, 61461-95-8, 89382-88-7, 977051-90-3

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

brown to red powder

MELTING POINT

 

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY

 

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pK

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 0, Flammability: 0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - Crocin

Wikipedia Linking - Crocin

Google Scholar Search - Crocin

Drug Information Portal (U.S. National Library of Medicine) - Crocin

PubChem Compound Summary - Crocin

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Crocin

http://www.ncbi.nlm.nih.gov/ -  Crocin

 

SALES SPECIFICATION

APPEARANCE

brown to red powder

ASSAY

95% min (Crocetin)

ASH

5% max

HEAVY METALS

10ppm max

AEROBIC PLATE

Total plate count: 1000CFU/G max
E. coli: Negative
Salmonella: Negative
Total Mold/Yeast: 100 cfu/g max

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

 

HAZARD CLASS

 

PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

Not a dangerous substance or mixture according to GHS (Globally Harmonised System). Eyes: May cause eye irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Ingestion: May be harmful if swallowed.

HAZARD CODES

 

RISK PHRASES

 

SAFETY PHRASES

 

 

PACKING

Preserve in light-resistant and well-closed containers