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EVANS BLUE |
| Synonyms. Evans blue; 4,4'-Bis(1-amino-8-hydroxy-2,4-disulpho-7-naphthylazo)-3,3'-bitolyl tetrasodium salt; 4,4'-Bis(7-(1-amino-8-hydroxy-2,4-disulpho)naphthylazo)- 3,3'-bitolyl tetrasodium salt; Azovan Blue; Blekit evansa; C.I. 23860; C.I. Direct Blue 53; C.I. direct blue 53 tetrasodium salt; Diamine Sky Blue FF; Diazobleu; Diazol Pure Blue BF; Direct Blue 53; Dye Evans Blue; Evablin; Evans blue sodium salt; Geigy Blue 536; Modr Evansova; Modr Prima 53; C.I. Direct Blue 53; C.I. Direct Blue 53 tetrasodium salt; Tetrasodium 6,6'-(3,3'-dimethyl-(1,1'-biphenyl)- 4,4'diyl)bis(azo)bis(4-amino- 5-hydroxy- 1,3-naphthalenedisulphonate); |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
314-13-6 |
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EINECS RN |
206-242-5 |
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FORMULA |
C34H24N6Na4O14S4 |
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MOLE WEIGHT |
960.81 |
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H.S CODE |
3204.14.3000 |
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SMILES |
c12c(c(cc(c1N)S([O-])(=O)=O)S([O-])(=O)=O)ccc(c2O)\N=N\c1c(cc(c2cc (c(\N=N/c3c(c4c(c(cc(c4N)S([O-])(=O)=O)S([O-])(=O)=O)cc3)O)cc2)C)cc1)C. [Na+].[Na+].[Na+].[Na+] |
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CLASSIFICATION |
Coloring agent, Azo dye |
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EXTRA NOTES |
An azo dye used in blood volume and cardiac output measurement by the dye dilution method. It is very soluble, strongly bound to plasma albumin, and disappears very slowly. |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
dark brown to black powder |
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MELTING POINT |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
280 g/l |
| SOLVENT SOLUBILITY |
Soluble in alcohol, acids, alkalies Insoluble in ether |
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VAPOR DENSITY |
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log P(octanol-water) |
0.71 |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pK |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 2, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Evans blue Wikipedia Linking - Evans blue Google Scholar Search - Evans blue Drug Information Portal (U.S. National Library of Medicine) - Evans blue PubChem Compound Summary - Evans blue KEGG (Kyoto Encyclopedia of Genes and Genomes) - Evans blue http://www.ncbi.nlm.nih.gov/ - Evans blue Material Safety Data Sheet - Evans blue EPA - Substance Registry Services - Evans blue |
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| SALES SPECIFICATION | |
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APPEARANCE |
dark brown to black powder |
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DYE CONTENT |
85% min |
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ABSORPTION |
650 nm λ max |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
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| HAZARD CLASS |
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| PACKING GROUP | |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
Toxic if swallowed. May cause cancer. Suspected of damaging the unborn child. Toxic by inhalation and in contact with skin. Danger of cumulative effects. Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion:May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Inhalation:May cause respiratory tract irritation. |
| SIGNAL WORD | Danger |
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PICTOGRAMS |
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HAZARD STATEMENTS |
H301-H360 |
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P STATEMENTS |
P201-P301 + P310-P308 + P313 |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
25-45 |
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SAFETY PHRASES |
53-45 |
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| PACKING |
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Preserve in light-resistant and well-closed containers |
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