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TRIOXSALEN |
| Synonyms. Trioxsalen; 2',4,8-Trimethylpsoralen; 2,5,9-Trimethyl-7H-furo(3,2-g)(1)benzopyran-7-one; 2,5,9-Trimethylpsoralen; 4,5',8-Trimethylpsoralen; 4,5',8-Trimethylpsoralene; 7-Oxo-2,5,9-Trimethyl-7H-furo(3,2-g)(1)benzopyron; Trimethylpsoralen; Trioxisaleno; Trioxysalene; Trioxysalenum; Trisoralen; 6-Hydroxy-beta,2,7-trimethyl-5-benzofuranacrylic acid delta-lactone; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
3902-71-4 |
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EINECS RN |
223-459-0 |
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FORMULA |
C14H12O3 |
|
MOLE WEIGHT |
228.24 |
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H.S CODE |
2932.20.2000 |
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SMILES |
c12c(cc3cc(oc3c1C)C)c(cc(o2)=O)C |
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CLASSIFICATION |
Coumarin, Dermatologic, Pigmentation agent |
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EXTRA NOTES |
Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo. |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
White to off-white crystalline powder |
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MELTING POINT |
234 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
Insoluble in cold water, sparingly soluble in boiling water |
| SOLVENT SOLUBILITY |
Slightly soluble in methanol, ethanol, chloroform. Soluble in methylene chloride. |
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VAPOR DENSITY |
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log P(octanol-water) |
3.7 |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pK |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 3, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Trioxsalen Wikipedia Linking - Trioxsalen Google Scholar Search - Trioxsalen Drug Information Portal (U.S. National Library of Medicine) - Trioxsalen PubChem Compound Summary - Trioxsalen Drug Bank - Trioxsalen KEGG (Kyoto Encyclopedia of Genes and Genomes) - Trioxsalen http://www.ebi.ac.uk/chebi/ - Trioxsalen http://www.ncbi.nlm.nih.gov/ - Trioxsalen Material Safety Data Sheet - Trioxsalen EPA - Substance Registry Services - Trioxsalen |
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| SALES SPECIFICATION | |
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APPEARANCE |
White to off-white crystalline powder |
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ASSAY |
99% min |
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MELTING POINT |
230 ~ 234 C |
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LOSS ON DRYING |
0.5% max |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
1759 |
| HAZARD CLASS |
8 |
| PACKING GROUP | I |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
Corrosive. Photosensitizer. Causes severe skin burns and eye damage. Suspected of causing cancer. Causes serious eye damage. |
| SIGNAL WORD | Danger |
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PICTOGRAMS |
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HAZARD STATEMENTS |
H314-H318-H351 |
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P STATEMENTS |
P280-P305 + P351 + P338-P310 |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
34-40 |
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SAFETY PHRASES |
26-36/37/39-45 |
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| PACKING |
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Preserve in light-resistant and well-closed containers |
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