TRIOXSALEN

Synonyms. Trioxsalen; 2',4,8-Trimethylpsoralen; 2,5,9-Trimethyl-7H-furo(3,2-g)(1)benzopyran-7-one; 2,5,9-Trimethylpsoralen; 4,5',8-Trimethylpsoralen; 4,5',8-Trimethylpsoralene; 7-Oxo-2,5,9-Trimethyl-7H-furo(3,2-g)(1)benzopyron; Trimethylpsoralen; Trioxisaleno; Trioxysalene; Trioxysalenum; Trisoralen; 6-Hydroxy-beta,2,7-trimethyl-5-benzofuranacrylic acid delta-lactone;

TRIOXSALEN

Click for original image

 

PRODUCT IDENTIFICATION

CAS RN

3902-71-4

EINECS RN

223-459-0

FORMULA

C14H12O3

MOLE WEIGHT

228.24

H.S CODE

2932.20.2000

SMILES

c12c(cc3cc(oc3c1C)C)c(cc(o2)=O)C

CLASSIFICATION

Coumarin, Dermatologic, Pigmentation agent

EXTRA NOTES

Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo.

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

White to off-white crystalline powder

MELTING POINT

234 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

Insoluble in cold water, sparingly soluble in boiling water

SOLVENT SOLUBILITY

Slightly soluble in methanol, ethanol, chloroform. Soluble in methylene chloride.

VAPOR DENSITY

 

log P(octanol-water)

3.7

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pK

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 3, Flammability: 0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - Trioxsalen

Wikipedia Linking - Trioxsalen

Google Scholar Search - Trioxsalen

Drug Information Portal (U.S. National Library of Medicine) - Trioxsalen

PubChem Compound Summary - Trioxsalen

Drug Bank -  Trioxsalen

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Trioxsalen

http://www.ebi.ac.uk/chebi/ -  Trioxsalen

http://www.ncbi.nlm.nih.gov/ -  Trioxsalen

Material Safety Data Sheet - Trioxsalen

EPA - Substance Registry Services - Trioxsalen

 

SALES SPECIFICATION

APPEARANCE

White to off-white crystalline powder

ASSAY

99% min

MELTING POINT

230 ~ 234 C

LOSS ON DRYING

0.5% max

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

1759

HAZARD CLASS

8

PACKING GROUP I

 

SAFETY INFORMATION

HAZARD OVERVIEW

Corrosive. Photosensitizer. Causes severe skin burns and eye damage. Suspected of causing cancer. Causes serious eye damage.

SIGNAL WORD Danger

PICTOGRAMS

HAZARD STATEMENTS

H314-H318-H351

P STATEMENTS

P280-P305 + P351 + P338-P310

EC DIRECTIVES

 

HAZARD CODES

RISK PHRASES

34-40

SAFETY PHRASES

26-36/37/39-45

 

PACKING

Preserve in light-resistant and well-closed containers