2-AMINO-2-METHYLPROPANOL

PRODUCT IDENTIFICATION
CAS NO. 124-68-5, 189832-99-3

2-AMINO-2-METHYLPROPANOL

EINECS NO. 204-709-8
FORMULA (CH3)2C(NH2)CH2OH
MOL WT. 89.14
H.S. CODE 2922.19.9590

UN NO.

  
TOXICITY Oral Rat LD50: 2900mg/kg
SYNONYMS 2-Amino-2-methylpropanol; 2-Amino-2-methyl-1-propanol;
Aminomethyl propanol; 1,1-Dimethyl-2-hydroxyethylamine; 2-Amino-1-hydroxy-2-methylpropane; 2-Amino-2,2-dimethylethanol; 2-Amino-2-methylpropan-1-ol; 2-Amino-2-methylpropanol; 2-Aminodimethylethanol; 2-Aminoisobutanol; 2-Hydroxymethyl-2-propylamine; 2-Methyl-2-aminopropanol; 2-Methyl-2-aminopropanol-1; beta-Aminoisobutanol; Hydroxy-tert-butylamine; ¤Ásobutanol-2-amine;
SMILES C(CO)(C)(C)N

CLASSIFICATION

Buffer, Neutralizing agent, Amino Alcohol

EXTRA NOTES

 EPA Pesticide Chemical Code 005801

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE clear semi solid
MELTING POINT 31 - 32 C
BOILING POINT 165 C
DENSITY

0.93

SOLUBILITY IN WATER Miscible (1.00E+06 mg/l at 25 C)
SOLVENT SOLUBILITY Soluble in alcohols
pKa 10.194 (Dissociation Constant at 10 C)
log Pow -0.74 (Octanol-water)
VAPOR PRESSURE 1(mmHg at 20 C)
HENRY LAW CONSTANT 6.48E-10 (atm-m3/mole at 25 C)
OH RATE CONSTANT 2.80E-11 (cm3/molecule-sec at 25 C Atmospheric )

REFRACTIVE INDEX

 1.447 - 1.449
VAPOR DENSITY  
NFPA RATINGS Health: 2; Flammability: 0; Reactivity: 0
FLASH POINT

67 C

STABILITY Stable under normal conditions

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Material Safety Data Sheet

Google Scholar Search

http://www.sigmaaldrich.com/
Application: Used in an efficient synthesis of 2-oxazolidinones via carbonylation with CO in the presence of salen-cobalt catalysts. Used to derivatize carboxylic acids for GC analysis and to synthesize 2-oxazolines for further transformations.

http://www.sigmaaldrich.com/
Useful pH Ranges of Selected Biological Buffers

http://www.scifun.org/
Chemical of the Week -- Biological Buffers
Many chemical reactions are affected by the acidity of the solution in which they occur. In order for a particular reaction to occur or to occur at an appropriate rate, the pH of the reaction medium must be controlled. Such control is provided by buffer solutions, which are solutions that maintain a particular pH. Biochemical reactions are especially sensitive to pH. Most biological molecules contain groups of atoms that may be charged or neutral depending on pH, and whether these groups are charged or neutral has a significant effect on the biological activity of the molecule. In all multicellular organisms, the fluid within the cell and the fluids surrounding the cells have a characteristic and nearly constant pH. This pH is maintained in a number of ways, and one of the most important is through buffer systems. Two important biological buffer systems are the dihydrogen phosphate system and the carbonic acid system.
SALES SPECIFICATION

APPEARANCE

 clear semi solid
TOTAL BASE

99.0% min

WATER

0.5% max

TRANSPORTATION
PACKING  
HAZARD CLASS  
UN NO.  
SAFETY INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/38-52/53, Safety Phrases: 61
PRICE INFORMATION