FLUORESCEIN

Synonyms. Fluorescein; 3',6'-Dihydroxyspiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one; CI 45350:1; D & C Yellow No. 7; 11712 Yellow; 3',6'-Dihydroxyfluoran; 3,6-Dihydroxyspiro(xanthene-9,3'-phthalide); 3,6-Fluorandiol; 9-(o-Carboxyphenyl)-6-hydroxy-3-isoxanthenone; C.I. 45350:1; C.I. Solvent Yellow 94; 9-(o-Carboxyphenyl)-6-hydroxy-3H-xanthen-3-one; Fluorescein Red; Fluorescein acid; Fluoresceine; Fluorescite; Hidacid fluorescein; Resorcinolphthalein; Solvent Yellow 94; Other RN: 126605-73-0, 213880-86-5

FLUORESCEIN

 

PRODUCT IDENTIFICATION

CAS RN

2321-07-5

EINECS RN

219-031-8

FORMULA

C20H12O5

MOLE WEIGHT

332.31

H.S CODE

2932.99.7000

SMILES

C12(c3c(C(=O)O2)cccc3)c2c(Oc3c1ccc(c3)O)cc(cc2)O

CLASSIFICATION

Contrast media, Diagnostic aid, Fluorescent Dye, Indicator, Luminescent agent

EXTRA NOTES

A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs and cosmetics.

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

orange to red powder

MELTING POINT

315 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY  

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pH

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 2,Flammability:1, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Fluorescein

Google Scholar Search - Fluorescein

Drug Information Portal (U.S. National Library of Medicine) - Fluorescein

PubChem Compound Summary - Fluorescein

KEGG (Kyoto Encyclopedia of Genes and Genomes) - Fluorescein

http://www.ebi.ac.uk/ - Fluorescein

http://www.ncbi.nlm.nih.gov/ - Fluorescein

http://toxnet.nlm.nih.gov/
Hazardous Substances Data Bank - Fluorescein

 

 

SALES SPECIFICATION

APPEARANCE

orange to red powder

MAX WAVE

490 - 493nm

LOSS ON DRYING

5.0% max

SOLUBILITY

passes test (in Ethanol)

ASH

0.5% max

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

Not regulated

HAZARD CLASS

 
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

Causes serious eye irritation. Target Organ Effect. Target Organs:Kidney

GHS

 

SIGNAL WORD

Warning

PICTOGRAMS

HAZARD STATEMENTS

H319

P STATEMENTS

P305 + P351 + P338

EC DIRECTIVES

 

HAZARD CODES

RISK PHRASES

36

SAFETY PHRASES

26

 

PACKING