HORDENINE

Synonym: 2-(4-Hydroxyphenyl)-N,N-dimethylethylamine; 4-(2-Dimethylaminoethyl)phenol; p-(2-Dimethylaminoethyl)phenol; N,N-Dimethyltyramine; p-Hydroxy-N,N-dimethylphenethylamine; Anhaline; Cactine; Eremursin; Peyocactine;

HORDENINE
 

PRODUCT IDENTIFICATION

CAS RN

 539-15-1

EINECS RN

 208-710-4

FORMULA

 C10H15NO

MOLE WEIGHT

 165.23

H.S CODE

 2922.29.6100

SMILES

 c1cc(O)ccc1CCN(C)C

CLASSIFICATION

Phenethylamine alkaloid

EXTRA NOTES

 A dimethyl tyramine; activates both nicotinic & adrenergic receptors.

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

 brown powder

MELTING POINT

 117 C

BOILING POINT

  

DENSITY

 1.27

SOLUBILITY IN WATER

 7000 mg/l
SOLVENT SOLUBILITY  

VAPOR DENSITY

 
OH RATE CONSTANT 1.21E-10 (cm3/molecule-sec at 25 C Atmospheric )
pH  

REFRACTIVE INDEX

  

FLASH POINT

 

 
STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

 Strong oxidizing agents
DECOMPOSITION PRODUCTS

Carbon oxides, Nitrogen Oxides, Hydrochloride gas
POLYMERIZATION Has not been reported

NFPA RATINGS

Health Hazard: 2, Fire: 0, Reactivity Hazard: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Hordenine

Google Scholar Search

Drug Information Portal (U.S. National Library of Medicine) - Hordenine

PubChem Compound Summary - Hordenine

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Hordenine

http://www.ebi.ac.uk/chebi/ - Hordenine

http://www.ncbi.nlm.nih.gov/ - Hordenine

Human Metabolome Database - Hordenine

http://wildflowerfinder.org.uk/
PHENYLETHYLAMINE ALKALOIDS: Hordenine is a Phenylethylamine not dissimilar to Dopamine. Hordenine exhibits anti-biotic and anti-bacterial properties and in mammals it stimulates the release of the hormone and neurotransmitter Noradrenaline (otherwise known as norepinephrine) which increases the heart-rate. Sprouting Barley seeds contain Hordenine in their roots as the main alkaloid. As an anti-biotic Hordenine has an inhibitory action on at least 18 strains of penicillin-resistant Staphylococcus bacteria. Hordenine is also produced by several cacti including the Peyote Cactus, and by some Acacia shrubs and trees.  The fungus also contains Tyramine, 4-hydroxyphenylethylamine, a naturally occurring monoamine which is derived from the amino acid Tyrosine. Tyramine acts as a catecholamine (such as Dopamine, Noradrenaline and Adrenaline) releasing agent but one which cannot cross the blood-brain barrier, limiting its effects to the body rather than having any psychoactive effects. Tyramine is contained in a lot of differing foods, including most hard cheeses, beans and green beans, chocolate, alcoholic drinks, fruits such as bananas, pineapple, Raspberry, peanuts, coconuts, yeast, etc. N-Methyltyramine is also found in plants such as Barley and Bitter Orange. It is yet another catecholamine releasing agent. It is a constituent of beer, which is made from malted Barley.

 

SALES SPECIFICATION

APPEARANCE

 brown powder

ASSAY

98.0% min

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

 Not regulated

HAZARD SYMBOL

 
PACKING GROUP

 

 

SAFETY INFORMATION

HAZARD OVERVIEW

OSHA Hazards:Harmful by ingestion., Skin sensitiser, Irritant

GHS

  

SIGNAL WORD

Warning

PICTOGRAMS

HAZARD STATEMENTS

H302 Harmful if swallowed.
H317 May cause an allergic skin reaction.
H319 Causes serious eye irritation.

PRECAUTIONARY STATEMENTS

P280 Wear protective gloves.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

SAFETY PHRASES

  

 

PACKING

 

 

PRICE INFORMATION