TROPINONE

3-Tropanone; Tropanon; Tropanone; 1alphaH,5alphaH-Tropan-3-one; 8-Methyl-8-azabicyclo(3.2.1) octan-3-one; 

TROPINONE

 

PRODUCT IDENTIFICATION

CAS RN

532-24-1

EINECS RN

208-530-6

FORMULA

C8H13NO

MOLE WEIGHT

139.19

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

yellowish to brown crystals

MELTING POINT

40 - 44 C

BOILING POINT

113 C at 25 mmHg

DENSITY

 

SOLUBILITY IN WATER

slightly soluble (soluble in ethanol, ether, acetone, benzene, slightly soluble in chloroform

pH

 

VAPOR DENSITY

 

REFRACTIVE INDEX

 

FLASH POINT

90 C

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBILITIES

Strong oxidizing agents
DECOMPOSITION PRODUCTS

Carbon oxides, Nitrogen oxides

POLYMERIZATION Has not been reported

NFPA RATINGS

Health Hazard: 1, Fire: 0, Reactivity Hazard: 0

 

SAFETY

HAZARD NOTES

Causes burns.

EYE

Causes eye burns.

SKIN

Causes skin burns.

INGESTION

Harmful if swallowed. Causes gastrointestinal tract burns.

INHALATION

Causes chemical burns to the respiratory tract.

CHRONIC

 

 

TRANSPORT AND REGULATORY INFORMATION

UN NO.

3259

HAZARD CLASS

8

PACKING GROUP

III

HAZARD SYMBOL

C

RISK PHRASES

22-34

SAFETY PHRASES

23-24/25

 

DESCRIPTION AND APPLICATION

Tropine is the tropane core structure part (nitrogenous bicyclic nucleus) and tropic acid is the ester part of atropine (a tropane alkaloid). Atropine is hydrolysed to tropine and tropic acid. Tropine also called tropanol (chemical designation: 8-Methyl-8-azabicyclo(3.2.1)octan-3-ol) is an alcohol which forms esters. There are stereoisomers endo- and exo- stereoisomers.
alpha-Tropanol

CAS RN

120-29-6
Trivial name Tropine
Systematic Name endo-8-Methyl-8-azabicyclo(3.2.1)octan-3-ol
Melting point 63 C
Boiling point 229 C

Natural esters

Hyoscyamine, Atropine

beta-Tropanol

CAS RN

135-97-7
Trivial name Pseudotropine
Systematic Name exo-8-Methyl-8-azabicyclo(3.2.1)octan-3-ol
Melting point 108 -109 C
Boiling point 240 - 241 C

Natural esters

Cocaine, Troparil

 

Tropeine is an ester of tropine, either a natural alkaloid derived from plants or semi-synthetic. The best known members of tropeine natural alkaloids are Hyoscyamine, Atropine, Scopolamine, Ecgonine, Cocaine.

Tropinone, bicyclic aminoketone, is a useful synthetic precursor in the preparation of many tropane ring compounds including tropine and atropine.

nor- is a chemical acronym and prefix to describe the lacking of methyl chains that are part of a larger molecule. Nortropine is a tropine compound lacking methyl chain at nitrogen carbon.

 

SALES SPECIFICATION

APPEARANCE

yellowish to brown crystals

ASSAY

99.0% min

MELTING POINT

40 - 44 C

 

PACKING

 

 

PRICE INFORMATION