p-ANISALDEHYDE

PRODUCT IDENTIFICATION

CAS NO. 123-11-5

p-ANISALDEHYDE

EINECS NO. 204-602-6
FORMULA CH3OC6H4CHO
MOL WT. 136.15

H.S. CODE

2912.49.1000

TOXICITY

Oral rat LD50: 1510 mg/kg
SYNONYMS 4-Anisaldehyde; p-Anisaldehyde; 4-Methoxybenzaldehyde;
Anisaldehí do; Anisaldé hyde; Aldé hyde anisique; Aldehí do; aní sico;p-Formylanisole; p-Anisic aldehyde; Aubepine; Obepin; Crategine; Other RN: 26249-15-0, 68894-36-0, 721942-53-6
SMILES c1(ccc(cc1)OC)C=O

CLASSIFICATION

 

EXTRA NOTES

Natural occurrence: Vanilla, fennel, star anise, cranberry, black currant, cinnamon, basil.

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

clear to slight yellow liquid

MELTING POINT

-1 C
BOILING POINT 249 - 250 C
SPECIFIC GRAVITY 1.19 - 1.20

SOLUBILITY IN WATER

2 g/l (soluble in alcohol, ether)
pH  
VAPOR DENSITY  

AUTOIGNITION

225 C

NFPA RATINGS

Health:2 Flammability: 1 Reactivity: 1

REFRACTIVE INDEX

1.571 - 1.574
FLASH POINT

116 C

STABILITY Stable under ordinary conditions. Air sensitive

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Google Scholar Search

Drug Information Portal (U.S. National Library of Medicine) -  p-Anisaldehyde

PubChem Compound Summary -  p-Anisaldehyde

IPCS INCHEM -   p-Anisaldehyde

KEGG (Kyoto Encyclopedia of Genes and Genomes) -   p-Anisaldehyde

http://www.ebi.ac.uk/ -   p-Anisaldehyde

http://www.ncbi.nlm.nih.gov/ -   p-Anisaldehyde

Material Safety Data Sheet

http://toxnet.nlm.nih.gov/
Hazardous Substances Data Bank -  p-Anisaldehyde

Local:
Anisole is one of the simplest aromatic compound to which ether group is linked. But it is different with aromatic compounds like furan where the oxygen is a part of the ring.  Anisole, C6H5OCH3 (methyl phenyl ether), is a clear liquid that is soluble in ether and alcohol insoluble in water boiling point 155 C. Anisole and its derivatives are used as solvents and in perfumery. Anisole can be obtained from anise seed. Anisic acid, p-methoxybenzoic acid, is a part of cresol class antiseptic compounds. It is also used as an insect repellent and ovicide. Anisole, anisic acid, and their derivatives are also widely used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals. p-Anisaldehyde, an aromatic aldehyde with mothoxy gruop, is a clear liquid may discolor to yellow on storage (limited shelf life for 6 months) melting at -1  C, boiling at 249.5 C insoluble in water, soluble in alcohol and ether. It is used in the synthesis of other organic compounds including pharmaceuticals (especially antihistamines), agrochemicals, dyes and plastic additives. It is an important intermediate for the processing of perfumes and flavouring compounds.

GENERAL DESCRIPTION OF BENZALDEHYDE: Benzaldehyde(also called Benzenecarbonal) is the simplest representative of the aromatic aldehydes. It is a colorless liquid aldehyde with a characteristic almond odor. It boils at 180° C, is soluble in ethanol, but is insoluble in water.Benzaldehyde is formed by partial oxidation of benzyl alcohol and readily oxidized to benzoic acid and is converted to addition products by hydrocyanic acid or sodium bisulfite. It is also prepared by oxidation of toluene or benzyl chloride or by treating benzal chloride with an alkali, e.g., sodium hydroxide. It is used chiefly in the synthesis of other organic compounds, ranging from pharmaceuticals to plastic additives and benzaldehyde is an important intermediate for the processing of perfume and flavouring compounds and in the preparation of certain aniline dyes It is the first step in the synthesis for fragrances. It undergoessimultaneous oxidation and reduction with alcoholic potassium hydroxide, giving potassium benzoate and benzyl alcohol. It is converted to benzoin with alcoholic potassium cyanide, with anhydrous sodium acetate and acetic anhydride, giving cinnamic acid. Compounds which do not have alpha-hydrogen atoms cannot form an enolate ion and do not undergo electrophilic alpha-substitution and aldol condensation. Aromatic aldehydes such as benzaldehyde and formaldehyde may undergo disproportionation in concentrated alkali (Cannizaro's reaction) one molecule of the aldehyde is reduced to the corresponding alcohol and another molecule is simultaneously oxidized to the salt of a carboxylic acid. The speed of the reaction depends on the substituents in the aromatic ring. Two different types of aldehydes (aromatic and aliphatic) can undergo crossing reaction to form fomaldehyde and aromatic alcohols.

SALES SPECIFICATION

APPEARANCE

Clear to slight yellow liquid
ASSAY

99.0% min

ISOMER

0.5% max

CHLORINE

20ppm max

MOISTURE

0.1% max

TRANSPORTATION
PACKING  
HAZARD CLASS  
UN NO.

Not regulated

SAFETY INFORMATION

HAZARD OVERVIEW

May cause respiratory tract irritation. Harmful if swallowed. Causes eye and skin irritation. Target Organs: Blood, kidneys, central nervous system, liver, eyes, skin.

GHS

 

SIGNAL WORD Warning

PICTOGRAMS

HAZARD STATEMENTS

H302

P STATEMENTS

P301 + P330 + P331

EC DIRECTIVES

 

HAZARD CODES

RISK PHRASES

36  Irritating to eyes
43  May cause sensitisation by skin contact

SAFETY PHRASES

24  Avoid contact with skin

PRICE INFORMATION