PRODUCT IDENTIFICATION

213-745-3

H.S. CODE

2933.99.7900

TOXICITY

5-Methoxy-2,3-benzopyrrole; Methoxy-5 indole; Indol-5-yl methyl ethe;

5-Methoxy-1H-indole; 5-Methoxyindole;

CLASSIFICATION 

EXTRA NOTES

PHYSICAL AND CHEMICAL PROPERTIES

white to grey crystalline powder 

MELTING POINT

56 - 58 C

SOLUBILITY IN WATER

REFRACTIVE INDEX

EXTERNAL LINKS & GENERAL DESCRIPTION

Google Scholar Search - 5-Methoxyindole

Drug Information Portal (U.S. National Library of Medicine) - 5-Methoxyindole

PubChem Compound Summary - 5-Methoxyindole

KEGG (Kyoto Encyclopedia of Genes and Genomes) - 5-Methoxyindole

http://www.ebi.ac.uk/ - 5-Methoxyindole

http://www.ncbi.nlm.nih.gov/ - 5-Methoxyindole

Material Safety Data Sheet

http://toxnet.nlm.nih.gov/
Hazardous Substances Data Bank - 5-Methoxyindole

Local:
Indole, benzopyrrole, is a yellow crystalline powder with unpleasant aroma. It has the pyrrole ring (five-membered unsaturated ring structure composed of four carbon atoms and one nitrogen atom) which is fused to benzene ring. There are tautomerer called indolenine (unsubstituted 3H-indole) and structural isomer, isoindole. But they are unstable. Indole occurs in some plants or in coal tar, and is formed in the intestine during putrefaction and by certain cultures of bacteria. it is commercially synthesized from phenylhydrazine and pyruvic acid.  Indole structure is a motif in nature. Prominent examples include tryptophan (aromatic side chain amino acid), serotonin (neurotransmitter), auxin (plant growth hormone), and indigo (plant colorant). One more interesting point is all these compounds have functional branches at 3 position. Indole is used in perfumery and in preparing tryptophan, one of the 20 amino acids commonly found in animal proteins. It has important application in the industry of plant growth. It is used to prepare indoleacetic acid (auxin) and other plant growth substances which help the development of roots in plant. It is used to make selective herbicides. Indole and its derivatives are widely used in making perfumes, dyes, agrochemicals and medicines. 

APPEARANCE

white to grey crystalline powder

98.0% min

LOSS ON DRYING

0.2% max

MELTING POINT

51 - 58 C

HAZARD OVERVIEW

May cause eye, skin, and respiratory tract irritation.

GHS

PICTOGRAMS

HAZARD STATEMENTS

H315-H319-H335

P STATEMENTS

P261-P305 + P351 + P338

RISK PHRASES

36/37/38

SAFETY PHRASES

26-36