p-TOLUQUINOLINE

PRODUCT IDENTIFICATION
CAS NO. 91-62-3

p-TOLUQUINOLINE
EINECS NO. 202-084-6
FORMULA C10H9N
MOL WT. 143.19

H.S. CODE

 2933.49

TOXICITY

 Oral rat LD50: 800 mg/kg
SYNONYMS 6-Methylquinoline; 6-Méthylquinoléine (French);
6-Methylchinolin (German); 6-Metilquinolina (Spanish);
SMILES  

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE

yellow liquid

MELTING POINT

 -22 - -20 C
BOILING POINT 259 - 263 C
SPECIFIC GRAVITY 1.062 - 1.063

SOLUBILITY IN WATER

 sparingly soluble
pH  
VAPOR DENSITY 4.94

REFRACTIVE INDEX

 1.612 - 1.617
NFPA RATINGS Health: 1; Flammability: 0; Reactivity: 0
FLASH POINT

109 C
STABILITY Stable under ordinary conditions. Light sensitive

GENERAL DESCRIPTION AND APPLICATIONS
Quinoline, 1-azanaphthalene, is an aromatic nitrogen compound characterized by a solid-ring structure contains a benzene fused to pyridine at two adjacent carbon atoms. (Pyridine is a ring structure compound of five carbon atoms with a nitrogen atom). Quinoline itself is the simplest member of the quinoline. It is a hygroscopic, yellowish oily liquid; slightly soluble in water, soluble alcohol, ether, carbon disulfide and readily in many organic solvents. It can be obtained by the distillation of coal tar. Quinoline can be prepared from aniline with acrolein under heated sulfuric acid (Skraup synthesis). Various quinoline compounds can be prepared by Skraup synthesis series of different oxidizing agents. Isoquinoline differs from quinoline in nitrogen position (at 2). Quinoline family compounds are widely used as a parent compound to make drugs (especially anti-malarial medicines), fungicides, biocides, alkaloids, dyes, rubber chemicals and flavoring agents. They have antiseptic, antipyretic, and antiperiodic properties. They are also used as catalyst, corrosion inhibitor, preservative, and as solvent for resins and terpenes. They are used in transition-metal complex catalyst chemistry for uniform polymerization and luminescence chemistry. They are used as antifoaming agent in refinery field. Quinaldine, 2-methylquinoline, is used as an anti-malaria and preparing other anti-malaria drugs. It is used in manufacturing oil soluble dyes, food colorants, pharmaceuticals, pH indicators and other organic compounds. Quinaldic Acid is a carboxylic acid substituted quinoline at 2 position, a catabolite of tryptophan (aromatic side chain amino acid). Quinazoline, diazanaphthalene at 1,3 positions, is used as a chemical intermediate for making medicines and other organic compounds. It is a fundamental structure in some antihypertensive agents such as prazosin and doxazosin which are peripheral vasodilator. Quinoxaline, diazanaphthalene at 1,4 positions, is used as a chemical intermediate for making fungicides and other organic compounds.
SALES SPECIFICATION

APPEARANCE

yellow liquid

Assay (GC)

 98.0% min
BOILING POINT 259 - 263 C
TRANSPORTATION
PACKING 200kgs in drum
HAZARD CLASS  
UN NO.

 
OTHER INFORMATION
Hazard Symbols: XN, Risk Phrases: 22-36/37/38, Safety Phrases: 45
FEMA No.: 2744