| PIPERACILLIN | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 61477-96-1
(Base) 59703-84-3 (Sodium salt) |
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| EINECS NO. | 262-811-8, 261-868-6 | |
| FORMULA | C23H27N5O7S | |
| MOL WT. | 517.56 | |
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H.S. CODE |
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TOXICITY |
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| SYNONYMS | Piperacillin anhydrous; | |
| 6-(D-(-)-alpha-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)phenylacetamido)penicillanic acid; 6-(((((4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl) amino)phenylacetyl) amino)- 3,3-dimethyl-7 -oxo-4-thia-1- azabicyclo(3.2.0)heptane-2-carboxylic acid; (2S-(2alpha, 5alpha,6beta(S*)))- 6-(((((4-Ethyl-2,3- dioxopiperazin-1-yl)carbonyl)amino) phenylacetyl) amino)- 3,3-dimethyl-7-oxo-4-thia-1- azabicyclo(3.2.0) heptane-2-carboxylic acid; 2S-(2-alpha,5-alpha,6-beta(S*)))-3,3-Dimethyl-6-(((((4-ethyl-2,3-dioxo-1-piperazinyl) carbonyl) amino)phenylacetyl)amino)-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane- 2-carboxylic acid; (2S,5R,6R)-6-[[(2R)-2-[(4-ethyl-2,3-dioxo-piperazine-1-carbonyl) amino]-2- phenyl-acetyl]amino]- 3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane- 2-carboxylic acid; Pipcil; | ||
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | white to off-white powder | |
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| SPECIFIC GRAVITY | ||
| SOLUBILITY IN WATER | freely soluble | |
| pH | ||
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REFRACTIVE INDEX |
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NFPA RATINGS |
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AUTOIGNITION |
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FLASH POINT |
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| STABILITY | Stable under normal conditions. | |
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GENERAL DESCRIPTION & APPLICATIONS |
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Piperacillin is a a semisynthetic broad-spectrum penicillin effective against a wide variety of gram-positive and gram-negative aerobic and anaerobic bacteria. It has 2,3-dioxo pierazinyl carbonyl moiety additionally in ampicillin structure. The chemical systematic designation is (2S-(2alpha,5alpha,6beta(S*)))-6-(((((4-Ethyl-2,3- dioxopiperazin-1-yl)carbonyl)amino) phenylacetyl)amino)- 3,3-dimethyl-7-oxo-4-thia-1- azabicyclo(3.2.0) heptane-2-carboxylic acid. Its main uses are in intensive care medicine, diabetes-related foot infections and empirical therapy in febrile neutropenia. The sodium salt of piperacillin is administered intramuscularly or intravenously. It is a white to off-white powder; freely soluble in water and in alcohol. The pH of an aqueous solution should be 5 to 7.Piperacillin is an ureidopenicillin antibiotic particularly effective against Pseudomonas infections. It is also used in combination with other antibiotics especially with tazobactam, a penicillanic acid sulfone derivative which acts as a beta-lactamase inhibitor similar to sulbactam, to widen the spectrum of activity. Some brand names include Pipracil (piperacillin alone), Tazocin, Tazocin, Tazocin, and Zosyn. |
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| SALES SPECIFICATION | ||
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APPEARANCE |
white to off-white powder | |
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IDENTIFICATION |
Passes tests |
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ASSAY |
900µ/mg | |
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WATER |
2.0 - 4.0% | |
| AMPICILLIN |
0.5% max |
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| OPTICAL ROTATION | +160° ~ +175° | |
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| PRICE INFORMATION | ||
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