L-EPICATECHIN

L-EPICATECHIN
PRODUCT IDENTIFICATION
CAS NO.	490-46-0
EINECS NO.	207-710-1
FORMULA	C₁₅H₁₄O₆
MOL WT.	290.27
H.S. CODE
TOXICITY
SOURCE
SYNONYMS	(-)-Epicatechin; cis-3,3',4',5,7-Pentahydroxyflavane;
2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol;
CLASSIFICATION	FLAVONOIDS /
PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE	yellow to greenish crystalline powder or needle
MELTING POINT	195 C
BOILING POINT	Decomposes
SPECIFIC GRAVITY
SOLUBILITY IN WATER	Soluble
pH
VAPOR DENSITY
AUTOIGNITION
NFPA RATINGS
REFRACTIVE INDEX
FLASH POINT
STABILITY	Stable under ordinary conditions. Hygroscopic, light sensitive.
GENERAL DESCRIPTION & APPLICATIONS
L-Epicatechin is a polyphenolic bioflavonoid derived form green tea. It, chemically 2-(3,4-Dihydroxyphenyl)- 3,4-dihydro-2H-1-benzopyran-3,5,7-triol, is a white powder melting at ca 240 C. Bioflavonoids are called phytochemicals, Vitamin P, and Vitamin C2. There are about 2000 known bioflavonoids including catechin, citrin, eriodictin, hesperetin, hesperidin, nobiletin, quercetin, rutin, sinensetin, and tangeretin. Vitamin P is not a dietary essential but is known to have the effect on capillary disorders. It increases the strength of the walls of the blood capillaries and regulates their permeability. It may have an contribution to the total antioxidant activity and detoxifiers. It may enhance the action of Vitamin C. It is considered that it lowers down cholesterol levels if it taken with Vitamin C. It is also know to have pharmacological action as an anti-inflammatory ,antihistaminic and antiviral agent.
SALES SPECIFICATION
APPEARANCE	white powder
ASSAY	90.0 % min
IDENTIFICATION	Pass
OPTICAL ROTATION	-53° ~ -55° (C=2 ACETONE/WATER 1:1)
HEAVY METALS	10ppm max
TRANSPORTATION
PACKING
HAZARD CLASS	not regulated
UN NO.
OTHER INFORMATION
`Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 26-36`
GENERAL DESCRIPTION OF FLAVONOID
Flavonoid is any member of a class of widely distributed biological natural products containing aromatic heterocyclic skeleton of flavan (2-Phenylbenzopyran) but no nitrogen in plants. Generally, flavonoids are biological pigments providing colours from red to blue in flowers, fruit and leaves. Besides their coloring in plants, flavonoids have important roles in the growth and development of plants; protection against UV-B radiation; forming antifungal barriers; antimicrobial, insecticidal and oestrogenic activities; plant reproduction. Flavonoids also exhibit a wide range of biological properties including anti-microbial, insecticidal and oestrogenic activities. Flavonoids are usually classified into main 6 subgroups as below plus flavans, neoflavonoids, flavonols, aurons, catechins according to the structural patterns. Flavonols (Hydroxy derivatives of flavone): Fisetin, Galangin, Kaempferide, Kaempferol, Morin, Myricetin, Myricitrin, Quercetin, Quercetrin, Rhamnetin, Robinin, Rutin, Spirenoside Flavones (skeleton: 2-phenylchromen-4-one): Apigenin, Baicalein, Chrysin, Diosmetin, Diosmin, Flavone, Luteolin, Rpoifolin,Tangeretin, Techtochrysin, Rhamnazin, Nobiletin, Natsudaidain. Isoflavones (skeleton: 3-phenylchromen-4-one): Daidzin, Genistein, Irilone, Luteone, Prunetin, Pratensein, Flavonones (derivation by reduction of the 2(3) C=C bond): Eriodictyol, Hesperidin, Hesperetin, Likvirtin, Naringin; Naringenin; Pinocembrin Flavanols (derivation by reduction of the keto group):(+)-Catechin, (+)-Gallocatechin, (-)-Epicatechin (EC), (-)-Epigallocatechin (EGC), (-)-Epicatechin 3-gallate (ECG), (-)-Epigallocatechin 3-gallate (EGCG), Theaflavin, Theaflavin 3-gallate, Theaflavin 3'-gallate, Theaflavin 3,3' digallate, Thearubigins Anthocyanidins (aglycones of the glycoside anthocyanins): Apigeninidin, Cyanidin, Delphinidin, Diosmetinidin, Guibourtinidin, Fisetinidin, Luteolinidin, Malvidin, Pelargonidin, Peonidin, Robinetinidin, Tricetinidin, Capensinidin, Petunidin, Europinidin, Aurentinidin, Columnidin, 5-Desoxy-malvidin, 5-Desoxy-peonidin, Hirsutinidin, Rosinidin
PRICE