2-AMINO-5-NITROBENZOPHENONE

2-AMINO-5-NITROBENZOPHENONE
PRODUCT IDENTIFICATION
CAS NO.	1775-95-7
EINECS NO.	217-207-9
FORMULA	H₂NC₆H₃(NO₂)COC₆H₅
MOL WT.	242.23
H.S. CODE
TOXICITY
SYNONYMS	(2-Amino-5-Nitrophenyl)Phenylmethanone;
SMILES
CLASSIFICATION
PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE	yellow to purple granular
MELTING POINT	159 - 164 C
BOILING POINT
SPECIFIC GRAVITY
SOLUBILITY IN WATER
pH
VAPOR DENSITY
REFRACTIVE INDEX
AUTOIGNITION	470 C
NFPA RATINGS
FLASH POINT
STABILITY	Stable under ordinary conditions
APPLICATIONS
Benzophenone, an aromatic ketones (diphenyl ketone), is an important compound in organic photochemistry and perfumery as well as in organic synthesis. It is a white crystalline substance with rose-like odor; insolube in water; melting point 49 C; boiling point 305 - 306 C. Benzophenone is used as a constituent of synthetic perfumes and as a starting material for the manufacture of dyes, pesticides and drugs (especially anxiolytic and hypnotic drugs). Benzophenone is used as a photoinitiator of UV-curing applications in inks, adhesive and coatings, optical fiber as well as in printed circuit boards. Photoinitiators are compounds that break down into free radicals upon exposure to ultraviolet radiation. Photoinitiators undergo a unimolecular bond cleavage upon irradiation to yield free radicals (benzoin esters; benzil ketals; alpha-dialkoxy acetophenones; alpha-hydroxy alkylphenones; alpha-amino alkylphosphine; acylphosphine oxides). Another type of photoinitiators undergo a bimolecular reaction where the excited state of the photoinitiator interacts with a second molecule (a coinitiator) to generate free radicals (benzophenones, amines; thioxanthones, titanocenes). Ultraviolet radiation has more energy than visible light, and thus degrade the physical properties such as the appearance of organic substances and plastics. Benzophenones can act as optical filters or deactivate substrate molecules that have been excited by light for the protection polymers and organic substances. They, cosmetic grades, are used as sunscreen agents to reduce skin damage by blocking UV-A, B. The prefix nitro- indicates the presence of NO₂^- radical, while nitrate refers to any salt or ester of nitric acid or the NO₃^- anion. Nitroso- is the prefix indicating presence of the group -NO and azo- is for -N=N- group. Some range of organic compounds containing nitrogen include nitro compounds (RNO₂ ), nitroso compounds (RNO), amines (R₃N ), amino acids, and natural alkaloids or nucleotides. The nitrogen ion in nitro compounds is trigonally planar with 120° angles. There are two resonance bonds so that the two oxygens are equivalent. Nitro compounds are strongly basic due to electron withdrawing both inductively and mesomerically. Historically, they are abundant in dyes and explosives. Nitro compounds, organic hydrocarbons having one or more NO₂ groups bonded via nitrogen to the carbon framework, are versatile intermediate in organic synthesis. Michael addition Reduction Henry Reaction (Nitro-aldol reaction) Nef reaction O-Alkylation Cycloaddition Substitution, Elimination, Conversion reaction Alkylation, Acylation, and Halogenation 2-Amino-5-Nitrobenzophenone is used as an intermediate for the synthesis of Nitrazepam which belong to a class benzodiazepines (anxiolytic drugs and hypnotic drugs).
SALES SPECIFICATION
APPEARANCE	yellow to purple granular
PURITY	99.0% min
MELTING POINT	157 C min
LOSS ON DRYING	0.5% max
TRANSPORTATION
PACKING	25kgs in drum
HAZARD CLASS
UN NO.
OTHER INFORMATION
`Hazard Symbols: XN, Risk Phrases: 22, Safety Phrases: 28A/28B/37/38/45`
PRICES