CEFAZEDONE

PRODUCT IDENTIFICATION

CAS NO. 56187-47-4 (base)
63521-15-3 (sodium) 

CEFAZEDONE

EINECS NO.  
FORMULA C18H15Cl2N5O5S3
MOL WT. 548.43

H.S. CODE

 

TOXICITY

 
SYNONYMS  
(6R-trans)-7-(((3,5-dichloro-4-oxo-1(4H)-pyridinyl) acetyl) amino)-3-(((5-methyl-1,3,4- thiadiazol- 2-yl)thio) methyl)-8 -oxo-5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid;

CLASSIFICATION

ANTIBOITICS / CEPHALOSPORINS /

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE White to yellowish white powder
MELTING POINT  
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 

REFRACTIVE INDEX

 
FLASH POINT

 

STABILITY Stable under ordinary conditions.

GENERAL DESCRIPTION & APPLICATIONS

Cephalosporin: any of a group of broad-spectrum derived from species of fungi of the genus Cephalosporium  and are related to the penicillins in both structure and mode of action but relatively penicillinase-resistant antibiotics. These antibiotics have low toxicity for the host, considering their broad antibacterial spectrum. They have the active nucleus of beta-lactam ring which results in a variety of antibacterial and pharmacologic characteristics when modified mainly by substitution at 3 and 7 positions. Their antibacterial activities result from the inhibition of mucopeptide synthesis in the cell wall. They are widely used to treat gonorrhea, meningitis, pneumococcal, staphylococcal and streptococcal infections. The cephalosporin class of antibiotics is usually divided into generations by their antimicrobial properties. Three generations of cephalosporins are recognized and the fourth has been grouped. Each newer generation of cephalosporins has broader range of activity against gram-negative organisms but a narrower range of activity against gram-positive organisms than the preceding generation. The newer agents have much longer half-lives resulting in the decrease of dosing frequency. Accordingly, the third-generation cephalosporins can penetrate into tissues well, and thus antibiotic levels are good in various body fluids. Cefazedone is a semisynthetic 1st generation cephalosporin antibiotic Inhibiting cell wall biosynthesis. It is used in the treatment of respiratory and urinary tract infections and is intended for oral administration. The chemical name is (6R-trans)-7-(((3,5-dichloro-4-oxo-1(4H)-pyridinyl) acetyl) amino)-3-(((5-methyl- 1,3,4-thiadiazol- 2-yl)thio) methyl)-8 -oxo-5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid.
SALES SPECIFICATION

APPEARANCE

White to yellowish white powder

IDENTIFICATION

Complies Test A,B

ASSAY

865 ug/mg min
MOISTURE 2.5% max

pH

4.0 - 6.0

IMPURITY

0.5% max (individual), 2.0% max (sum)

TRANSPORTATION
PACKING

5kgs - 20kgs

HAZARD CLASS  
UN NO.  
OTHER INFORMATION
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