CYCLOHEXIMIDE

PRODUCT IDENTIFICATION

CAS NO. 66-81-9, 21059-09-6

CYCLOHEXIMIDE

EINECS NO. 200-636-0
FORMULA C15H23NO4
MOL WT. 281.35

H.S. CODE

 

TOXICITY

 
SYNONYMS Actidione; neocycloheximide;
[1S-[1alpha(S),3alpha,5beta]]-4-[2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-2, 6- Piperidinedione; 3-(2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide; 3-((R)-2-((1S,3S,5S)-3,5- dimethyl-2- oxocyclohexyl)-2-hydroxyethyl)glutarimide; 4-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2- hydroxyethyl]-2,6- piperidinedione;
SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white to yellowish crystalline powder
MELTING POINT

119 - 121 C

BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER 2-5 g/100ml (soluble in alcohol, chloroform, ether, acetone)
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS  

REFRACTIVE INDEX

 
FLASH POINT

 

STABILITY

Stable under ordinary conditions.

GENERAL DESCRIPTION & APPLICATIONS

Cycloheximide (also known as actidione) is used as an selective antibiotic. It inhibits the protein synthesis (DNA-dependent RNA) of saprobic fungi eukaryotes. by binding with the 80S ribosome, while inactive against dermatophytes and systemic fungi. But it is not active against prokaryotes. it is used in the selection of wild type genes. It is used as a plant growth regulator to stimulate ethylene production. It is used as a rodenticide and other animal pesticide. It is used as a media to detect to unwanted bacteria by suppressing yeasts and molds in beer fermentation. Some products such as nisin have this effective function as a preservative for food and beverage. But cycloheximide is highly toxic is not suitable for human use as a therapeutic antibiotic. Agricultural application also is decreasing due to the health risks. It is used as an agent effective against psoriasis.
Antipsoriatic

CAS RN

Acitretin 55079-83-9
Isoacitretin 69427-46-9
Anthralin 480-22-8
Azaribine 2169-64-4
Calcipotriene 112965-21-6
Calcitriol 32222-06-3
Cedefingol 35301-24-7
Cycloheximide 66-81-9
Cyclosporine 59865-13-3
Etretinate 54350-48-0

Fumaric acid

110-17-8 

Hydroxyurea 127-07-1
Liarozole fumarate 145858-52-2
Lonapalene 91431-42-4
Methotrexate 59-05-2
Methoxsalen 298-81-7
Moxilubant maleate 147398-01-4
Nimidane 50435-25-1
Peldesine 133432-71-0
Safingol hydrochloride 139755-79-6
Safingol 15639-50-6
Tacalcitol 57333-96-7
Tazarotene 118292-40-3
Tepoxalin 103475-41-8
Trioxsalen 3902-71-4
5-Methoxypsoralen 484-20-8
6-Thioguanine 154-42-7 
SALES SPECIFICATION

APPEARANCE

white to yellowish crystalline powder

ASSAY

95.0 % min

LOSS ON DRYING

0.5% max

MELTING POINT

119 - 121 C

TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: T+ N, Risk Phrases: 28-51/53-61-68, Safety Phrases: 45-53-61
PRICES

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