ALOE-EMODIN

PRODUCT IDENTIFICATION
CAS NO.

481-72-1

ALOE-EMODIN

EINECS NO. 207-571-7
FORMULA C15H10O5
MOL WT. 270.24

H.S. CODE

  

TOXICITY

  
SYNONYMS Rhabarberone; Aloe emodin; 3-Hydroxymethylchrysazin;

1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone; 1,8-Dihydroxy-3-(hydroxymethyl)anthracene- 9,10-dione; 1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione;

DERIVATION

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE orange crystalline powder
MELTING POINT 223 - 224 C
BOILING POINT

 

RELATIVE DENSITY  
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

REFRACTIVE INDEX

 

NFPA RATINGS

  

AUTOIGNITION

 

FLASH POINT

 

STABILITY Stable under normal conditions.

GENERAL DESCRIPTION & APPLICATIONS
Rhein (1,8-Dihydroxyanthraquinone-3-carboxylic acid) is an anthraquinone-related compound found in several plants especially Rhamnus frangula. It is an enzyme inhibitor that binds to enzymes and decrease their activity, which leads killing a pathogen or correcting a metabolic imbalance. Natural poisons are often enzyme inhibitors that have evolved to defend a plant or animal against predators. Many insecticides (such as malathion), herbicides (glyphosate), and disinfectants (triclosan) are enzyme inhibitors. They are also designed as part of pharmacology and biochemistry to treat disease. They are used as tool in toxicity studies.

Diacerein, diester of rhein, is metabolized to active rhein. It is a slow acting symptomatic drug used in the treatment of osteoarthritis by inhibiting interleukin-1 and and metalloproteinases. But it has no effect of cyclooxygenase.

Closely related compounds with Rhein are Aloin (an anthraquinone glycoside) and Emodin (lack of sugar molecule) which have three hydroxyl groups on anhraquinone skeleton. They are isolated from various species of aloe. Aloin containing anthraquinone moiety is a natural pigment and has cathartic properties.

  • Aloin: 10-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
  • Emodin: 1,3,8-Trihydroxy-6-methyl-9,10-anthraquinone
  • Aloe-emodin: 1,3,8-trihydroxyanthraquinone

Emodin Molecules

Product

CAS RN.
4-Hydroxyemodin

476-46-0
Aloe-emodin 481-72-1
omega-Hydroxyemodin 481-73-2
Emodin anthrone 491-60-1
Emodin 518-82-1
Physcione 521-61-9
2-Hydroxyemodin 641-90-7
Aloin 1415-73-2
Questin 3774-64-9
Aloe emodin anthrone 6247-99-0
Alloin 8015-61-0
7-Hydroxyemodin 10228-40-7
5-Hydroxyemodin 20324-66-7
Emodin-8-glucoside 23313-21-5
Cascaroside 50814-04-5
4-Hydroxyaloin 74390-86-6
Alophen 76741-91-8
Aloe-emodin dianthrone diglucoside 99520-79-3
SALES SPECIFICATION

APPEARANCE

 orange crystalline powder

ASSAY

98.0% min

HEAVY METALS

10ppm max
RESIDUE ON IGNITION

0.1% max
LOSS ON DRYING 0.2% max
TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.

 

OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 26-36
PRICE INFORMATION

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