ALOPERINE

ALOPERINE

PRODUCT IDENTIFICATION

CAS NO.

56293-29-9

ALOPERINE

EINECS NO.

FORMULA

C₁₅H₂₄N₂

MOL WT.

232.36446

H.S. CODE

TOXICITY

SYNONYMS

(7-alpha,9-alpha)-9-De-2-piperidinyl-16,17-didehydroormosanine;

(7-alpha,9-alpha)-16,17-Didehydro-9-de-2-piperidinylormosanine;

CLASSIFICATION

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

yellow crystalline powder

MELTING POINT

69 - 71 C

BOILING POINT

SPECIFIC GRAVITY

SOLUBILITY IN WATER

VAPOR DENSITY

REFRACTIVE INDEX

NFPA RATINGS

AUTOIGNITION

FLASH POINT

STABILITY

Stable under normal conditions.

GENERAL DESCRIPTION & APPLICATIONS

Quinolizidine and isoquinoline alkaloids are a widely distributed, heterogeneous group of alkaloids with members of each group having known toxicity to humans and domestic animals.
Cytisine, a tricyclic quinolizidine alkaloid found in Baptisia, Cytisus, Laburnum, and Sophora species, has nicotinelike effects on the gastrointestinal (GI) tract and the central nervous system (CNS). These plants may be smoked recreationally for their stimulant effects and mild hallucinogenic properties. Mescal bean may have been used by Native American peoples for ceremonial and medicinal purposes. Sophora root is used in traditional Chinese medicine where it is known as "Ku Shen" and is used to treat dysentery, scabies, itchy rashes including eczema, skin lesions, jaundice, edema, urinary dysfunction, and vaginal discharge.
Lupinus species contain sparteine, a tetracyclic quinolizidine alkaloid, and lupinine, a bicyclic quinolizidine alkaloid. Lupinus species are broadly divided into bitter lupins that contain high levels of alkaloids in their seeds, and sweet lupins that contain lower levels of alkaloids and are cultivated for human consumption. Sweet lupins do contain sparteine and lupinine and must be soaked in water to prevent toxicity following ingestion. These two alkaloids are also found in other genera.(http://emedicine.medscape.com/)

Many mono- and di- quinolizidine alkaloids show pharmacological actions such as antifungal, antimicrobial, analgesic, antiulcerogenic and anticancer. They are core pharmaceutical compositions of traditional Chinese medicines.

Quinolizidine alkaloid	CAS RN.
Sparteine	90-39-1
Cytisine	485-35-8
Lupinine	486-70-4
1-Epilupinine	486-71-5
Matrine	519-02-8
Multiflorine	529-80-6
Angustifoline	550-43-6
Lupanine	550-90-3
Aphyllidine	643-32-3
Baptifoline	732-50-3
Retamine	2122-29-4
Lusitanine	5121-36-8
Sophocarpine	6483-15-4
Allomatrine	6783-60-4
Sophoramine	6882-66-2
Sophoridin	6882-68-4
Oxymatrine	16837-52-8
Aloperine	56293-29-9

SALES SPECIFICATION

APPEARANCE

yellow crystalline powder

ASSAY

95.0% min

MELTING POINT

> 65 C

HEAVY METALS

20ppm max

TRANSPORTATION

PACKING

HAZARD CLASS

UN NO.

PRICE INFORMATION