ACETOACETIC-O-TOLUIDIDE (AAOT)

ACETOACETIC-o-TOLUIDIDE
PRODUCT IDENTIFICATION
CAS NO.	93-68-5
EINECS NO.	202-267-0
FORMULA	CH₃COCH₂CONHC₆H₄CH₃
MOL WT.	191.23
H.S. CODE	2924.29
TOXICITY	Oral rat LD50: 1600 mg/kg
SYNONYMS	2'-Methylacetoacetanilide; AAOT; Acetoacet-o-Toluidine;
N-(2-methylphenyl)-3-oxo-Butanamide; N-Acetoacetyl-ortho-toluidine; 2'-Methylacetoacetanilide; 2-Acetoacetylaminotoluene; 2'-Methylacetoacetanilid (German); 2'-metilacetoacetanilida (Spanish); 2'-methylacétoacétanilide (French);
SMILES
CLASSIFICATION	ACETOACETIC ACID DERIVATIVES /
PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE	white to off white powder
MELTING POINT	103 C
BOILING POINT	Decomposes
SPECIFIC GRAVITY	1.062
SOLUBILITY IN WATER	Slightly
AUTOIGNITION	516 C
NFPA RATINGS	Health: 2 ; Flammability: 1; Reactivity: 0
REFRACTIVE INDEX
FLASH POINT	143 C
STABILITY	Stable under normal temperatures and conditions
APPLICATIONS
Acetoacetic acid derivatives with heterocycles have versatile applications including making agrochemicals, dyes, pigments, pharmaceuticals including vitamins, and stabilizers for PVC and polyester. They are used as solvents for fragrances. Acetoacetic acid and its esters contain active methylene groups which have relatively acidic alpha-protons due to H atoms adjacent to two carbonyl groups. The reactivity of its methylene group provide the sequence of reactions of alkylation, hydrolysis of the esters and decarboxylation resulting in substituted ketones. The methylene group can be reacted to form amino-carbonyl compounds. Acetoacetates are important aliphatic parts adjoining azo dyes and pigments. Acetoacetic acid is unstable and decompose to acetone and carbon dioxide at room temperature. Aacetoacetate is one of ketone bodies which are the end-products of rapid or excessive fatty acid breakdown in the human body. Acetoacetates have a reactive hydrogen atom on the carbon alpha to both carbonyl groups. It undergoes Knoevenagel condensation reaction as a reactant to forms a large class of target products including amino acids, drugs, colorants, lacquers, perfumes, and plastics. Alone, it is used as a flavoring agent and a solvent. Knoevenagel condensation is a nucleophilic addition of a reactive hydrogen atom at 1,3-diketone compounds to a carbonyl group, followed by an dehydration reaction. 1,3-Diketone compounds (beta-ketones) include malonic acid, diethyl malonate, Meldrum's acid, and acetoacetic acid derivatives. AAOT is used in manufacturing agricultural chemicals, coating materials, dyes and pigments, pharmaceuticals, co-promoters for polymers. Anilide is a amide in which one or more hydrogens are replaced by phenyl; having the C₆H₅NH₂-group.
SALES SPECIFICATION
APPEARANCE	White to off white powder
PURITY (G.C.)	99.0% min
MELTING POINT	103 C min
MOISTURE	0.2% max
IRON	0.5ppm max
TRANSPORTATION
PACKING	25kgs in bag
HAZARD CLASS
UN NO.
OTHER INFORMATION
`Hazard Symbols: XN, Risk Phrases: 22, Safety Phrases: 24/25-28A-37-45`
PRICE INFORMATION