NORTROPINE

NORTROPINE

PRODUCT IDENTIFICATION

CAS NO.

538-09-0, 14383-51-8 (hydrochloride)

NORTROPINE

EINECS NO.

238-356-6 (hydrochloride)

FORMULA

C₇H₁₃NO

MOL WT.

127.18

H.S. CODE

SYNONYMS

2,3-Dihydro-3-hydroxynortropidine; 3-alpha-Nortropanol;

1alpha-H,5alpha-H-Nortropan-3alpha-ol; 3-Hydroxynortropane; Nortropenol; Nortropin; Tropigenin; Tropigenine; 1alphaH,5alphaH-Nortropan-3alpha-ol; endo-8-Azabicyclo (3.2.1) octan-3-ol; (1R,5S)-8-Azabicyclo[3.2.1]octan-3-ol;

CLASSIFICATION

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

white to slightly yellow crystalline powder

MELTING POINT

180 - 182 C

BOILING POINT

SPECIFIC GRAVITY

SOLUBILITY IN WATER

Soluble

VAPOR DENSITY

AUTOIGNITION

NFPA RATINGS

REFRACTIVE INDEX

FLASH POINT

STABILITY

Stable under ordinary conditions.

GENERAL DESCRIPTION

Tropine is the tropane core structure part (nitrogenous bicyclic nucleus) and tropic acid is the ester part of atropine (a tropane alkaloid). Atropine is hydrolysed to tropine and tropic acid. Tropine also called tropanol (chemical designation: 8-Methyl-8-azabicyclo(3.2.1)octan-3-ol) is an alcohol which forms esters. There are stereoisomers endo- and exo- stereoisomers.

alpha-Tropanol
CAS RN	120-29-6
Trivial name	Tropine
Systematic Name	endo-8-Methyl-8-azabicyclo(3.2.1)octan-3-ol
Melting point	63 C
Boiling point	229 C
Natural esters	Hyoscyamine, Atropine
beta-Tropanol
CAS RN	135-97-7
Trivial name	Pseudotropine
Systematic Name	exo-8-Methyl-8-azabicyclo(3.2.1)octan-3-ol
Melting point	108 -109 C
Boiling point	240 - 241 C
Natural esters	Cocaine, Troparil

Tropeine is an ester of tropine, either a natural alkaloid derived from plants or semi-synthetic. The best known members of tropeine natural alkaloids are Hyoscyamine, Atropine, Scopolamine, Ecgonine, Cocaine.

Tropinone, bicyclic aminoketone, is a useful synthetic precursor in the preparation of many tropane ring compounds including tropine and atropine.

nor- is a chemical acronym and prefix to describe the lacking of methyl chains that are part of a larger molecule. Nortropine is a tropine compound lacking methyl chain at nitrogen carbon.

SALES SPECIFICATION

APPEARANCE

white to slightly yellow crystalline powder

ASSAY

98.0% min

MELTING POINT

180 - 182 C

TRANSPORTATION

PACKING

HAZARD CLASS

UN NO.

PRICE